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작성자 Leesa 작성일24-05-09 01:11 조회50회 댓글0건관련링크
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이름 : Leesa
이메일 : leesahightower@hotmail.co.uk 연락처 : 예식일 : Esults are going to be accessible in 2016. Phages may be an aged but 문의내용: Esults will be obtainable in 2016. Phages may be Marimastat an previous but modern way within the war against antimicrobial resistance. Antimicrobial resistance can be the foremost trigger of mortality in 2050.References Character Opinions,Quantity fourteen, August 2015 The Lancet infectious illnesses,Volume 15, No. twelve, p1384?385, December 2015 Character Opinions Microbiology, AOP, released on line 9 November 2015; doi:ten.1038/nrmicroP110 Antibiotic dosing faults in critically ill individuals with severe sepsis or septic shock H. Al-Dorzi, A. Eissa, S. Al-Harbi, T. Aldabbagh, R. Khan, Y. Arabi King Saud bin Abdulaziz University for Health Sciences , Riyadh, Saudi Arabia Critical Care 2016, 20(Suppl 2):P110 Introductions: Powerful antibiotic treatment, which can be described as being the well timed administration of the antibiotic to which the causative microorganism is inclined using the appropriate dose, continues to be involved with improved outcomes in extreme sepsis or septic shock. However, antibiotic dosing faults aren't unusual. This analyze evaluated the frequency as well as danger aspects of antibiotic dosing glitches in patients with significant sepsis or septic shock. Techniques: This was a possible observational review PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/22993420 of all adult sufferers with intense sepsis or septic shock who have been admitted to your ICU in between 01/10/2013 and 30/04/2014. Working with Micromedex as the reference, the doses of administered intravenous antibiotics about the to start with ICU day have been as opposed to your advised doses and have been categorized as under-dosed, over-dosed or ideal. We excluded antibiotics which typically won't have to have dose adjustment. Multivariate logistic regression evaluation was performed to evaluate predictors of antibiotic dosing error (under- or over-dosing). Age, gender, height, pounds, long-term cardiovascular and renal ailments, approximated glomerular filtration rate and existence of shock were the independent variables. Results: Over the examine period, 189 sufferers had severe sepsis (sixty two ) or septic shock (38 ). We evaluated 263 antibiotic prescriptions. Most (62 ) people gained proper antibiotic doses. Nonetheless, 39 (21 ) individuals have been under-dosed, 30 (sixteen ) were being over-dosed, and three (2 ) had mixture of over-dosing and under-dosing. Septic patients with chronic heart problems (p = 0.035) and long-term renal failure (p = 0.021) ended up more very likely to have antibiotic dosing problems. Even so, respiratory failure, liver failure, immunodeficiency condition and diabetes mellitus were not obviously affiliated with dposing problems. Vancomycin was affiliated with the maximum dosing error fee (43 ). One other antibiotics (pipercillin/tazobactam, meropenem, imipenem, ceftriaxone, ciprofloxacin, colistin and gentamicin) were being dosed appropriately in >70 of prescriptions. The multivariate assessment showed the estimated glomerular filtration fee was the only real variable related with dosing error (odds ratio, 0.ninety eight for each 1 ml/min increment; 95 confidence interval, 0.97-0.ninety nine). Conclusions: Antibiotic dosing faults, which include under- and over-dosing, were being popular in individuals with significant sepsis or septic shock. Vancomycin had the very best charge of inappropriate dosing. Decrease glomerular filtration level was a big predictor of dosing mistake and may be routinely viewed as for antibiotic dosing. P111 Does empiric antifungal remedy improve survival in septic critically sick people? PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/9547713 (immunocompromised excluded) A. Trifi, S. Abdellatif , F. Daly, R. Nasri , S. Ben Lakhal University medical center centre of l. a. Rabta. , Tuni.
이메일 : leesahightower@hotmail.co.uk 연락처 : 예식일 : Esults are going to be accessible in 2016. Phages may be an aged but 문의내용: Esults will be obtainable in 2016. Phages may be Marimastat an previous but modern way within the war against antimicrobial resistance. Antimicrobial resistance can be the foremost trigger of mortality in 2050.References Character Opinions,Quantity fourteen, August 2015 The Lancet infectious illnesses,Volume 15, No. twelve, p1384?385, December 2015 Character Opinions Microbiology, AOP, released on line 9 November 2015; doi:ten.1038/nrmicroP110 Antibiotic dosing faults in critically ill individuals with severe sepsis or septic shock H. Al-Dorzi, A. Eissa, S. Al-Harbi, T. Aldabbagh, R. Khan, Y. Arabi King Saud bin Abdulaziz University for Health Sciences , Riyadh, Saudi Arabia Critical Care 2016, 20(Suppl 2):P110 Introductions: Powerful antibiotic treatment, which can be described as being the well timed administration of the antibiotic to which the causative microorganism is inclined using the appropriate dose, continues to be involved with improved outcomes in extreme sepsis or septic shock. However, antibiotic dosing faults aren't unusual. This analyze evaluated the frequency as well as danger aspects of antibiotic dosing glitches in patients with significant sepsis or septic shock. Techniques: This was a possible observational review PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/22993420 of all adult sufferers with intense sepsis or septic shock who have been admitted to your ICU in between 01/10/2013 and 30/04/2014. Working with Micromedex as the reference, the doses of administered intravenous antibiotics about the to start with ICU day have been as opposed to your advised doses and have been categorized as under-dosed, over-dosed or ideal. We excluded antibiotics which typically won't have to have dose adjustment. Multivariate logistic regression evaluation was performed to evaluate predictors of antibiotic dosing error (under- or over-dosing). Age, gender, height, pounds, long-term cardiovascular and renal ailments, approximated glomerular filtration rate and existence of shock were the independent variables. Results: Over the examine period, 189 sufferers had severe sepsis (sixty two ) or septic shock (38 ). We evaluated 263 antibiotic prescriptions. Most (62 ) people gained proper antibiotic doses. Nonetheless, 39 (21 ) individuals have been under-dosed, 30 (sixteen ) were being over-dosed, and three (2 ) had mixture of over-dosing and under-dosing. Septic patients with chronic heart problems (p = 0.035) and long-term renal failure (p = 0.021) ended up more very likely to have antibiotic dosing problems. Even so, respiratory failure, liver failure, immunodeficiency condition and diabetes mellitus were not obviously affiliated with dposing problems. Vancomycin was affiliated with the maximum dosing error fee (43 ). One other antibiotics (pipercillin/tazobactam, meropenem, imipenem, ceftriaxone, ciprofloxacin, colistin and gentamicin) were being dosed appropriately in >70 of prescriptions. The multivariate assessment showed the estimated glomerular filtration fee was the only real variable related with dosing error (odds ratio, 0.ninety eight for each 1 ml/min increment; 95 confidence interval, 0.97-0.ninety nine). Conclusions: Antibiotic dosing faults, which include under- and over-dosing, were being popular in individuals with significant sepsis or septic shock. Vancomycin had the very best charge of inappropriate dosing. Decrease glomerular filtration level was a big predictor of dosing mistake and may be routinely viewed as for antibiotic dosing. P111 Does empiric antifungal remedy improve survival in septic critically sick people? PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/9547713 (immunocompromised excluded) A. Trifi, S. Abdellatif , F. Daly, R. Nasri , S. Ben Lakhal University medical center centre of l. a. Rabta. , Tuni.
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